DISTINCT RESTING-STATE EFFECTIVE CONNECTIVITY OF LARGE-SCALE NETWORKS IN FIRST-EPISODE AND RECURRENT MAJOR DEPRESSION DISORDER: EVIDENCE FROM THE REST-META-MDD CONSORTIUM

Distinct resting-state effective connectivity of large-scale networks in first-episode and recurrent major depression disorder: evidence from the REST-meta-MDD consortium

IntroductionPrevious studies have shown disrupted effective connectivity in the large-scale brain networks of individuals with major depressive disorder (MDD).However, it is unclear whether these changes differ between first-episode drug-naive MDD (FEDN-MDD) and recurrent MDD (R-MDD).MethodsThis study utilized resting-state fMRI data from 17 sites

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Linking experienced barriers during daily travel and transport poverty in peripheral rural areas: the case of Zeeland, the Netherlands

People living in peripheral orly ethereal plane rural areas are often considered to be prone to transport poverty and inaccessibility to activities.Previous identifications of transport poverty have mainly relied on accessibility measures based on land-use and transport data.However, such measures may be very different from how people themselves pe

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